Hyperbaric Oxygen Therapy: New Breakthroughs and Future Prospects in the Treatment of Solid Tumors
Solid tumors are one of the most common types of cancer, and their incidence is increasing year by year globally, bringing great pain and economic burden to patients.
Although modern medicine has made remarkable progress in cancer diagnosis and treatment, traditional therapies, although capable of controlling tumor growth and spread to a certain extent, are often accompanied by serious side effects.
Therefore, exploring new treatment methods to improve the therapeutic effects of solid tumors has become an important topic in current medical research.
Solid tumors, “bombs” lurking in the body
Solid tumors are solid masses occurring in human tissues and organs, usually formed by the proliferation of tumor cells. Symptoms vary depending on the type, location and size of the tumor. Common symptoms include lumps, pain, bleeding, weight loss and fatigue. Solid tumors form as a result of a combination of factors. Genetic factors, chronic inflammation, environmental exposures, lifestyle, hormone levels, abnormalities in immune function, and changes in the tumor microenvironment may all play an important role in tumor development and progression. Understanding these causes can help to take targeted preventive measures to reduce the risk of solid tumors.
Conventional therapies & limitations
Currently, conventional treatments for solid tumors mainly include surgery, chemotherapy, radiotherapy and immunotherapy.
Surgery A radical cure is achieved by removing the tumor tissue. However, surgery cannot completely remove the tumor cells, especially for tumors that have already metastasized, the effect of surgery is limited. Chemotherapy The use of chemicals to kill tumor cells, but its side effects, such as nausea, vomiting, hair loss, bone marrow suppression, etc., and the tumor cells are easy to develop drug resistance. Radiotherapy Using radiation to kill tumor cells, but it causes more damage to the surrounding normal tissues and is not effective for certain types of tumors. So, is there a safer, more convenient and comfortable solution?
Hyperbaric Oxygen Therapy, “New Hope” for Solid Tumor Care
In recent years, with the continuous progress of science and technology, an emerging solid tumor prevention and treatment program has gradually come into the public's field of vision - Hyperbaric Oxygen Therapy (HBOT) As a non-invasive new adjuvant naturopathic treatment, HBOT has played a positive role in cancer disease management.
What is hyperbaric oxygen therapy?
The inhalation of pure oxygen or highly concentrated oxygen in an environment higher than one atmosphere (1.0 ATA) is called hyperbaric oxygen, and the method of using hyperbaric oxygen to treat diseases is called hyperbaric oxygen therapy. Hyperbaric oxygen therapy, is through the pressurized room to the confined space delivery of high concentration of oxygen (air pressure in the confined space is higher than the normal atmospheric pressure) to assist in regulating the body.
Mechanism of hyperbaric oxygen therapy for solid tumors
Hyperbaric oxygen therapy mainly works through the following aspects:
Improvement of tumor microenvironment: Hyperbaric oxygen can reduce fibronectin and collagen I in the tumor area, thus improving the tumor microenvironment. This improvement helps drugs penetrate more deeply and accumulate in the tumor, enhancing the therapeutic effect. Inhibition of Cancer Stem Cells and Metastasis: Hyperbaric oxygen can directly inhibit the activity of cancer stem cells, as well as inhibit the ability of cancer to metastasize. This is important for preventing tumor recurrence and spread. Breaking immunosuppression: A hypoxic environment leads to immunosuppression, enabling tumor cells to evade the immune system. Hyperbaric oxygen therapy can break this state of immune suppression and enhance the ability of the immune system to recognize and attack tumor cells, thus improving the effect of immunotherapy.
Hyperbaric oxygen therapy, as an emerging means of cancer treatment, shows great potential due to its multifaceted mechanism of action. It not only improves the tumor microenvironment and enhances drug penetration and accumulation, but also directly inhibits cancer stem cells and metastasis, breaks down immune suppression, and synergistically increases oxidative stress, thus improving the overall effect of cancer treatment. A number of clinical trials on hyperbaric oxygen are currently underway, and we expect that this innovative treatment method will bring more hope and opportunities to cancer patients and inject new vitality into the field of cancer treatment.
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